DNA methylation is a frequent epigenetic mechanism that participates in transcriptional repression.Variations in DNA methylation with respect to gene expression are constant, and, for unknown reasons, some genes with highly methylated promoters are sometimes overexpressed.In this study we have analyzed the expression and methylation patterns of tho
Abstract Axon degeneration and functional decline in myelin diseases are often attributed to loss of myelin but click here their relation is not fully understood.Perturbed myelinating glia can instigate chronic neuroinflammation and contribute to demyelination and axonal damage.Here we study mice with distinct defects in the proteolipid protein 1 g
Background: The use of sagittal abdominal diameter (SAD) has been proposed for screening cardio-metabolic risk factors; however, its accuracy can be influenced by the choice of thresholds values.Aim: To determine the SAD threshold values for cardio-metabolic risk factors in Mexican adults; to assess whether parallel and serial SAD testing can impro